07/2019
The first reconstitution of a mammalian mRNA transport system done by Sebastian Bauman is online:
https://www.biorxiv.org/content/10.1101/701250v1
In the movie below we see beta2B-tubulin RNA (red) transported by a reconstituted APC-kinesin-2 complex on microtubules (grey). The lower panel shows single-particle tracking of the transported RNAs (circle color around spots: total spot intensity). We used intensity measurements to show that one kinesin transports dimeric APC which binds one RNA per APC monomer.
03/2019
Stay tuned for news on the first reconstituted axonal mRNA transport system
11/2018
We are looking for PhD students to work with systems and biochemical approaches to understand how RBPs work together and how neurons can generate their mRNA distribution patterns. Please check out the Jobs-Section. And apply through CRG’s PhD Fellowship programme.
09/2018
Our new paper describing two new matrix screening techniques is out !
We can now do many cool things as simultaneous interaction-domain determination and many-by-many protein-RNA interaction screening!
03/2018
Julia Grawenhoff got a Severo-Ochoa FPI PhD fellowship to join our lab in spring 2018. Welcome Julia !
01/2017
Sebastian Baumann got a Juan de la Cierva postdoc fellowship to continue his promising work in our lab. Congratulations Sebastian!
06/2016
Artem joined the lab. He won a LaCaixa-PhD fellowship and he will focus on developing ex-vivo tools to understand mRNP dynamics and function. Welcome, Artem !
03 / 2016
Our lab won an HFSP Young Investigator Grant together with the labs of Ivo Telley, Martin Loose and Timothy Saunders.
11 / 2015
Andrea joins the lab on a Severo Ochoa PhD fellowship – Welcome Andrea
10 / 2015
We were awarded the Europa Excelencia grant of the Spanish MINECO
06 / 2015
Sebastian Baumann got a Marie-Curie fellowship – Congratulations !
04 / 2015
Lorenzo joined the lab to carry out a 6 month Leonardo Student project – Welcome !!!
01 / 2015
SebastianB joined the lab as a Postdoc – Welcome Sebastian !
09 /2014
Bogumilla started her PhD in our lab, supported by an LaCaixa fellowship, welcome !
