Our mission is to understand basic principles of RNA-cytoskeleton interactions. These interactions are essential for the regulation of localised gene expression – a mechanism allowing cells to configure different cellular regions for specialised functions. Our approach combines systematic discovery strategies with biophysical bottom-up reconstitution techniques. We look at the cellular machines which we aim to understand with the eyes of an engineer. By analysing the functionalities of the engine parts and their connection to other parts we build functional complexes. This teaches us how activities observed in cells are generated through the dynamic interplay of specialised, cellular building blocks.
The MaurerLab is located at CRG Barcelona within the Cell and Developmental Biology department. We are equipped with our own multi-color Total-Internal-Reflection-Microscope which is an essential part of the quantitative approach to biology we take in the lab.