PROJECT DESCRIPTION

My research interest is focused on the mechanisms and interplay of dendritic RNA localization and translational control. The main questions are (i) What is the minimal set of proteins necessary and sufficient for kinesin dependent, dendritic RNA transport, (ii) how are transported mRNAs translationally regulated? To address these questions, I apply in vitro approaches.

 

CV

Since June 2015: Marie Curie postdoctoral fellow

From January 2015: Postdoc in the laboratory of Sebastian Maurer at the Center for Genomic Regulation (CRG), Barcelona, Spain

2013 – 2014: Postdoc in the laboratory of Prof. Michael Feldbrügge, Institute for Microbiology, Heinrich-Heine University Düsseldorf, Germany

2007 – 2013: PhD in Cell Biology/Microbiology in the laboratory of Prof. Michael Feldbrügge at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany

2002 – 2007: Diploma studies in Genetics, Philipps University of Marburg, Germany

 

PUBLICATIONS

First author Publications

Baumann S, Zander S, Feldbrügge M (2016) Live cell imaging of septin dynamics in Ustilago maydis. Methods in Molecular Biology 136:143-59

Zander S*, Baumann S*, Weidtkamp-Peters S, Feldbrügge M (2016) Endosomal assembly and transport of heteromeric septin complexes promote septin cytoskeleton formation. Journal of Cell Science  129(14):2778-92 (*equal contribution)

Baumann S, Takeshita N, Grün N, Fischer R,, Feldbrügge M (2015) Live cell imaging of endosomal trafficking in fungi. Methods in Molecular Biology 1270:347-63

Baumann S, König J, Koepke J, Feldbrügge M (2014) Endosomal transport of septin mRNA and protein indicates local translation on endosomes and is required for correct septin filamentation. EMBO Reports 15(1): 94-102 21

Baumann S, Pohlmann T, Jungbluth M, Brachmann A, Feldbrügge M (2012) Kinesin-3 and dynein mediate microtubule-dependent co-transport of mRNPs and endosomes. Journal of Cell Science 125: 2740-2752 21

König J*, Baumann S*, Koepke J, Pohlmann T, Zarnack K, Feldbrügge M (2009) The fungal RNA-binding protein Rrm4 mediates long-distance transport of ubi1 and rho3 mRNAs. EMBO Journal 28: 1855-1866 (*equal contribution) 21

Co-author Publications

Pohlmann T, Baumann S, Haag C, Albrecht M, Feldbrügge M (2015) A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking. eLife 18;4.

Jansen RP, Niessing D, Baumann S, Feldbrügge M (2014) mRNA transport meets membrane traffic. Trends in Genetics 30(9): 408-417 review article

Pöhlmann J, Risse C, Seidel C, Pohlmann T, Jakopec V, Walla E, Ramrath P, Takeshita N, Baumann S, Feldbrügge M, Fischer R, Fleig U (2014) The Vip1 inositol polyphosphate kinase family regulates polarized growth and modulates the microtubule cytoskeleton in fungi. PLoS Genetics 10(9):e1004586

Vollmeister E, Schipper K, Baumann S, Haag C, Pohlmann T, Stock J, Feldbrügge M (2012) Fungal development of the plant pathogen Ustilago maydis. FEMS Microbiology Reviews 36: 59-77 review article

Vollmeister E, Haag C, Zarnack K, Baumann S, König J, Mannhaupt G, Feldbrügge M (2009) Tandem KH domains of Khd4 recognise AUACCC and are essential for regulation of morphology as well as pathogenicity in Ustilago maydis. RNA 15: 2206-2218

Feldbrügge M, Zarnack K, Vollmeister E, Baumann S, Koepke J, König J, Münsterkötter M, Mannhaupt G (2008) The posttranscriptional machinery of Ustilago maydis. Fungal Genetics and Biology 45: 40-46 review article

König J, Julius C, Baumann S, Homann M, Göringer HU and Feldbrügge M (2007) Combining SELEX and yeast three-hybrid system for the in vivo selection and classification of RNA aptamers. RNA 13: 614-622